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How is hereditary spastic paraplegia (HSP) treated?

The stiffness or spasticity, as neurologists call it, can be treated symptomatically with muscle relaxers which can be taken orally like baclofen, dantrolene, valium, or zanaflex. But sometimes the medication might work better when delivered directly to the cerebrospinal fluid through an intrathecal baclofen pump. Physical therapy with a focus on stretching can help prevent the development of painful contractures. There is no current treatment to get at the underlying cause of HSP.

There are no specific treatments to prevent, slow, or reverse HSP. Symptomatic treatments used for spasticity are sometimes helpful. Regular physical therapy is important for muscle strength and to preserve the range of motion.

This answer is based om source infomation from the National Institute of Neurological Disorders.

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