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Who should not take promethazine?

Although promethazine may benefit individuals with allergies, colds, motion sickness, nausea and vomiting, certain individuals should not take the medication. Because promethazine may cause serious respiratory depression, individuals with compromised respiratory function, such as those with COPD or sleep apnea, should not take the medication. Promethazine may increase the risk of seizures and should not be given to individuals with a history of seizures or epilepsy. Because promethazine impairs blood cell production in bone marrow, individuals who are undergoing chemotherapy or radiation, or who have depressed bone marrow production, should not take the medication. Children under two years of age should not use promethazine because of the risk of breathing difficulties and potential death. Precautions should be taken when giving promethazine to any child, regardless of age.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.