What is the most important information I should know about sulfasalazine?

Before taking sulfasalazine, talk to your doctor about your complete medical history.

Some medical conditions, including porphyria and stomach, bowel and urinary tract obstructions, may prevent you from being able to take sulfasalazine. Some medications interact with sulfasalazine. Tell your doctor about all of the prescription medications, over-the-counter medications, vitamins and herbal supplements you are taking.

While taking sulfasalazine, people often become more sensitive to sunlight and are more likely to suffer a sunburn. While taking sulfasalzine, your urine and skin may turn an orange or yellow color.  Men should discuss with their doctor the potentially negative, though temporary, effect of sulfasalazine on sperm count. Due to a possible risk of birth defects, women should take the drug during pregnancy only if it is clearly needed. 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.