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What is omeprazole and sodium bicarbonate?

Omeprazole and sodium bicarbonate are combined to form the medications called Zegerid and Zegerid OTC. The combination is used to treat disorders caused by an overproduction of stomach acid, such as stomach or intestinal ulcers, esophagitis or inflammation of the esophagus and gastroesophageal reflux disease (GERD). Omeprazole works by decreasing the amount of stomach acid your stomach produces. Sodium bicarbonate acts as an antacid. It works by raising the pH level in your stomach so that the omeprazole does not break down in your stomach acid.

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