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What is Cholbam?

Cholbam is a bile acid intended for the treatment of genetic illnesses that prevent the creation of the body's own cholic acid. Normally the liver creates cholic acid from cholesterol, but patients with disorders like Zellweger syndrome, or single peroxisomal enzyme / transporter deficiencies (PEDs), are unable to do this. Primary bile acids like cholic acid aid fat digestion and absorption, necessary for building nerves and brain tissue, and for proper organ function. Without primary bile acids, infants with these inherited diseases cannot develop properly. Older patients whose disease manifests itself later in life may develop partial paralysis, Addison's disease, and other signs. Cholbam may be used in patients as young as three weeks. It is administered as a capsule taken once or twice daily with food.

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