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Who should not use promethazine?

Anyone who is allergic to promethazine should avoid using it. Also, it may cause harmful reactions in people with certain medical conditions, including cancer, high blood pressure, glaucoma, seizures, diabetes, liver, heart or kidney disease, difficulty with breathing or urination, stomach problems, an overactive thyroid or a bone marrow disorder. Similarly, promethazine may interact poorly in people taking certain medications, such as muscle relaxers, painkillers, MAO inhibitors, blood thinners, drugs that make you sleepy (sleeping pills, sedatives, etc.), medicines that treat high blood pressure, Parkinson's disease, depression, anxiety, ulcers, motion sickness, irritable bowel disease, urinary disorders, restless leg syndrome, pituitary gland tumors or mental illness.

It should not be taken with other medications that treat cold and allergy symptoms. Additionally, if you are pregnant or breastfeeding you should alert your doctor, as promethazine may cause damage to the developing fetus or nursing child's health. People who drink alcohol frequently cannot do so while on this medication.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.