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Who should not use promethazine suppositories?

Anyone who is allergic to promethazine should avoid using them. Also, they may cause harmful reactions in people with certain medical conditions, including: cancer, high blood pressure, glaucoma, seizures, diabetes, liver, heart or kidney disease, difficulty with breathing or urination, stomach problems, an overactive thyroid or a bone marrow disorder.  Similarly, promethazine suppositories may interact poorly in people taking certain medications, such as muscle relaxers, painkillers, MAO inhibitors, epinephrine (adrenaline), blood thinners and drugs that make you sleepy (sleeping pills, sedatives, etc). They can also interact badly with medicines that treat high blood pressure, Parkinson's disease, depression, anxiety, ulcers, motion sickness, irritable bowel disease, urinary disorders, restless leg syndrome, pituitary gland tumors, spasms or mental illness.

You should also avoid taking them with other medications that treat cold and allergy symptoms. Additionally, if you are pregnant or breastfeeding you should alert your doctor, as promethazine may cause damage to the developing fetus or nursing child's health. People who drink alcohol frequently cannot do so while on this medication. Finally, children under two years of age should not use promethazine.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.