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Does hyoscyamine sulfate medication interact with other drugs?

Hyoscyamine sulfate extended release tablets can interact with other medications. Some medications like antacids can reduce your body's ability to absorb your hyoscyamine sulfate medication. Other medications can have similar of more severe drug interactions. The following drugs are known to interact with hyoscyamine sulfate extended release tablets:

  • antidepressants, including: amitriptyline, amoxapine (Ascendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), or trimipramine (Surmontil)
  • monoamine oxidase inhibitors (MAOIs), including: isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate)
  • phenothiazines, including: chlorpromazine (Thorazine), fluphenazine (Prolixin), mesoridazine (Serentil) perphenazine (Trilafon), prochlorperazine (Compazine), thioridazine (Mellaril), or trifluperazine (Stelazine)

Hyoscyamine sulfate extended release tablets can interact with other Parkinson's disease medications such as amantadine (Symmetrel), which an antiviral medication and glutamate blocking drug. Some medications like haloperidol (Haldol), which are used to treat mental disorders like schizophrenia, can also interact with hyoscyamine sulfate extended release medication. Before taking hyoscyamine, it's important to tell your doctor about all medication you're taking, including over-the-counter drugs, vitamins, and herbal supplements.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.