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How should I take promethazine suppositories?

Promethazine suppositories are designed to be inserted into the rectum and should never be taken orally or vaginally. The suppository form of promethazine is typically prescribed to treat nausea and vomiting when an individual is unable to swallow or retain the oral tablet form. Wash your hands prior to touching the suppository to prevent infection. Remove the foil wrapper and run cold water over the suppository to moisten it. Lie on your side and gently insert the suppository one-half to one inch inside the rectum using one finger. If the suppository is too moist to easily insert into your rectum, it may be placed in the refrigerator for 30 minutes prior to insertion. Using a water-based lubricant may ease insertion. Oil-based lubricants should not be used because it may interfere with absorption of promethazine into the system. Remain lying down for 15 minutes. If possible, do not have a bowel movement for at least one hour after inserting the medication.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.