Can glycopyrrolate interact with other medications or foods?

The ulcer medication glycopyrrolate (Robinul) may interact with other medications, potentially causing problems. Before taking glycopyrrolate give your doctor a list of all medicines (prescription and non-prescription) and dietary and herbal supplements you take, and be sure to mention the following:
  • other anticholinergics, including ipratropium
  • medicines to treat depression, anxiety or other mental illness
  • other ulcer drugs
  • sleeping pills or tranquilizers
  • drugs to treat motion sickness
  • drugs to treat Parkinson's disease
  • medicines for irritable bowel disease
  • seizure medications
  • drugs to treat urinary problems
  • potassium supplements
  • the heart medicine digoxin
Alcohol may worsen drowsiness that's a common side-effect of glycopyrrolate, so you may need to curtail drinking while taking this drug.

If your child is taking glycopyrrolate as Cuvposa (an oral solution to treat excessive drooling), note that eating high-fat foods may affect how well his body absorbs the drug, so give him the medicine at least one hour before or two hours after a meal.

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