What is amitriptyline for the treatment of fibromyalgia?

Donna Hill Howes, RN
Family Practitioner

Amitriptyline is a tricyclic antidepressant drug that works through its effects on brain chemicals. It is used to treat depression. It can also reduce pain and fatigue and improve sleep. Amitriptyline is considered first-line treatment for fibromyalgia, but is not FDA-approved for this use.

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