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What if I have a serious allergic reaction to Lyrica?

If you have a serious allergic reaction to Lyrica (pregabalin), a prescription drug used to relieve nerve pain, treat fibromyalgia and manage seizures, stop taking it right away and call your doctor. A reaction might include swelling of your mouth, face or neck; a rash, blisters, hives or a hive-like swelling under the skin (called angioedema); or trouble breathing. The This sort of reaction can be life-threatening.

Before you start taking Lyrica, tell your doctor if you have had a reaction like this in the past. He or she will use caution in deciding whether it's safe to prescribe Lyrica for you. Don't take this drug if you have previously had an allergic reaction to Lyrica, pregabalin or any other ingredients in Lyrica.

Before you start taking Lyrica, you should also give your doctor a complete medical history, including any health conditions you might have. Give him or her a list of all of your medications, whether they're prescription or over-the-counter, as well as dietary and herbal supplements. Once you're on Lyrica, do not start taking another drug or supplement without talking with your doctor first. Some medications can raise your risk of having an allergic reaction to Lyrica.
Dawn Marcus
Neurology
Lyrica (pregabalin) is one of three drugs approved for treating fibromyalgia (the others are duloxetine and milnacipran). Anyone having an allergic reaction to Lyrica should stop taking it and let their doctor know right away. In some cases, emergency treatment is needed for allergic reactions.

Lyrica (pregabalin), a prescription drug used to help control seizures, treat fibromyalgia and manage nerve pain, can cause a dangerous, even life-threatening, allergic reaction. You should stop taking it and call your doctor right away if you notice:

  • swelling of your face, mouth, lips, tongue, gums, throat or neck
  • trouble breathing
  • hives, blisters or a rash

You should not take this drug if you’ve ever had an allergic reaction to Lyrica, pregabalin or any of Lyrica’s ingredients. Before you start taking Lyrica, give your doctor a complete medical history, and be sure to mention if you’ve ever had a condition known as angioedema, swelling that occurs just below the skin. This is a type of allergic reaction. You should also tell him or her about all your medications, whether prescription or over-the-counter, as well as any supplements you take. Some medications may increase the likelihood that you’ll have an allergic reaction to Lyrica.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.