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What are the approved doses of Lyrica for the treatment of fibromyalgia?

The U.S. Food and Drug Administration (FDA) recommends 300 to 450 milligrams (mg) of Lyrica per day for the treatment of fibromyalgia, divided into two doses. People who have fibromyalgia typically start out on a lower dose of Lyrica (usually 75 mg twice a day) for a week or so. If they tolerate the drug well, their doctor may increase their dosage to 150 mg twice a day. People who are experiencing enough benefits from Lyrica may stay at this dose. The dosage may be raised to 450 mg per day (two doses of 225 mg) for someone who needs more relief from pain or from other fibromyalgia symptoms.
To help manage pain and improve functioning in people with fibromyalgia, the U.S. Food and Drug Administration (FDA) recommends a dose of 300 to 450 milligrams (mg) of Lyrica daily. However, you and your doctor can work together to determine the best dose for you.

Typically, people with fibromyalgia begin by taking 75 mg of Lyrica twice a day for about a week while being monitored carefully by a doctor. If you are able to tolerate this amount of Lyrica, your doctor may increase your dose to 150 mg twice a day, or 300 mg per day total. If this dose doesn't relieve your fibromyalgia symptoms adequately, your doctor may increase your dose to 225 mg twice a day, or 450 mg per day total. If you have kidney problems, your doctor may recommend lower doses of Lyrica.

Talk to your doctor or your pharmacist for more information about the benefits and side effects of Lyrica.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.