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What are the risks of taking anti-seizure drugs during pregnancy?

Dawn Marcus
Neurology
In general, anti-seizure drugs are limited to the treatment of seizure or epilepsy disorders during pregnancy because studies show a small increase in birth defect risks with this group of medications.

Gabapentin (Neurontin) may be used in early pregnancy and then discontinued in the third trimester because of possible interference with the baby's bone development. No increased risk for miscarriage, low birth weight, or birth defects have been identified in women using abapentin during pregnancy. While this is encouraging, gabapentin has not been used in enough pregnancies to know that it is safe to use.

Both topiramate (Topamax) and valproate (Depakene, Depacon) have been linked to an increased risk of birth defects.
The Woman's Migraine Toolkit: Managing Your Headaches from Puberty to Menopause (A DiaMedica Guide to Optimum Wellness)

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The Woman's Migraine Toolkit: Managing Your Headaches from Puberty to Menopause (A DiaMedica Guide to Optimum Wellness)

Migraines are a common, controllable type of headache that affects one in every six women, more than 20 million in the United States alone. The Woman’s Migraine Toolkit helps readers take charge of...

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.