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What is unexplained infertility?

It is estimated that up to 10 percent of couples with infertility will have no explanation, a situation that is frustrating for both the couple and their doctor. When the male has normal sperm and the female has open tubes, ovulatory cycles and normal hormone profile, doctors have to look beyond the usual causes.

The good news for couples with unexplained infertility is that this often represents a form of inflammation that can be diagnosed and treated effectively. Fertility specialists usually recommend that women with unexplained infertility have a careful evaluation for endometriosis. In one ongoing study of couples with unexplained infertility, researchers found that the vast majority have stage I or II (minimal or mild) of the disease. Once diagnosed, most of these couples conceive on their own without further treatment.

Unfortunately, many couples do not get early diagnosis and therefore may have problems even during in vitro fertilization (IVF). Diagnosing infertility first and then starting treatment can make a big difference in success rates for couples with unexplained infertility.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.