Which drugs may interact with conjugated estrogen injections?

Conjugated estrogens for injection (brand name Premarin) is indicated for short-term use, however, the injection may interact with certain medications or the outcome of laboratory tests. Several medicines can prevent the estrogens from working properly or vice versa. The medications include: certain birth control pills, aromatase inhibitors used to fight cancer, barbiturates, antibiotics like rifamycin, herbal medicines like St. John's Wort and anticonvulsants like phenytoin. Similarly, some medications may increase the risk of the injection's side effects. These drugs include HIV medicines like ritonavir, antibiotics like erythromycin and clarithromycin and antifungal medications like ketoconazole and itraconazole. Tell your doctor of all the medications, vitamins, supplements and over-the-counter products you are taking.                 

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