What should I know about estradiol before taking it?

Before taking estradiol, you should know that a history of stroke or blood clots, abnormal vaginal bleeding, hormone-related cancers like uterine or breast cancer, or circulation problems may prevent you from taking this drug. If you are pregnant or plan to become pregnant, you cannot use estradiol as it may cause birth defects in the fetus. The use of estradiol can increase the risk of developing endometrial hyperplasia, which is a condition that can cause uterine cancer. Using estradiol for long periods of time can increase your risk for heart attack, stroke and breast cancer.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.