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What are side effects of estradiol acetate?

Serious side effects of estradiol acetate include:
  • allergic reaction (itchiness, hives, swelling of the airways, rash)
  • cough, particularly coughing blood
  • chest constriction
  • sudden vision problems
  • flu-like symptoms
  • weight gain
  • confusion, strange behavior/thoughts
  • pain, swelling or soreness in your stomach
  • lump in breast, nipple discharge
  • acne, skin color changes
  • extremely painful headaches
  • voice changes
  • difficulty speaking or comprehending
  • dark urine
  • light-colored stools
  • yellowish eyes/skin
  • mood changes, memory loss
  • swelling or soreness in the calf
  • problems walking, dizziness, lack of coordination
  • right upper stomach pain
  • trouble catching your breath
  • sudden lack of strength or feeling of numbness
  • unusual vaginal bleeding
Less serious side effects include:
  • acne, altered skin color
  • ankle/feet swelling
  • breast swelling
  • increased or decreased interest in sex
  • unable to perform sexually, trouble having an orgasm
  • feeling tired
  • headaches, dizziness
  • hair loss, unusual hair growth
  • vaginal irritation

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.