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What side effects of estradiol should I report to my doctor?

Estradiol may cause a variety of mild side effects. If any become severe, tell your doctor immediately. In particular, report any of the following:
  • bulging eyes
  • yellowed skin or eyes
  • itching, hives, skin rash or blisters
  • loss of appetite
  • fever
  • joint pain
  • stomach problems such as tenderness, pain or swelling
  • poor muscle control
  • swollen eyes, face, lips, tongue, throat, hands, feet, ankles or lower legs
  • hoarseness, wheezing or difficulty breathing or swallowing

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.