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What are the side effects of Estrace vaginal cream?

Serious side effects of Estrace vaginal cream:
  • allergic reaction (itchiness, hives, swelling of the airways, rash)
  • chest constriction
  • sudden vision problems
  • flu-like symptoms
  • weight gain
  • confusion, strange behavior/thoughts
  • pain, swelling or soreness in your stomach
  • lump in breast, nipple discharge
  • acne, skin color changes
  • extremely painful headaches
  • voice changes
  • difficulty speaking or comprehending
  • dark urine
  • light-colored stools
  • yellowish eyes/skin
  • swelling or soreness in the calf
  • problems walking, dizziness, lack of coordination
  • right upper stomach pain
  • trouble catching your breath
  • sudden lack of strength or feeling numb
  • unusual vaginal bleeding
Less serious side effects include:
  • acne, altered skin color
  • ankle/feet swelling
  • breast swelling
  • feeling more hungry or thirsty than usual
  • feeling tired
  • headache, dizziness
  • lessened sex drive, trouble having an orgasm
  • losing some hair
  • mood changes
  • vaginal irritation

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.