Advertisement

What are the risks of using an estradiol transdermal system?

The estradiol transdermal system consists of "patches" that contain estradiol, which is a form of the hormone estrogen. Taking medications that contain estrogen increases your risk for developing endometrial cancer, which is cancer of the uterus (or womb). This risk appears to be greatest in women who use estrogen for more than one year. If you use an estradiol transdermal system, your doctor may prescribe another type of medication known as a progestin. Studies show that using estrogen with or without progestin may increase your risk for the following:
  • heart attacks
  • strokes
  • blood clots in the lungs, legs or elsewhere
  • breast cancer
  • ovarian cancer
  • gallbladder disease
Also, using estrogen with progestin may increase your risk of dementia, or loss of memory and other mental functions. Talk to your doctor and weigh the benefits of using an estradiol transdermal system against these known risks.

Continue Learning about Estrogen

How can applying estrogen help treat overactive bladder?
Donna Hill Howes, RNDonna Hill Howes, RN
Women need estrogen to help maintain strength and flexibility of tissues around the bladder and ...
More Answers
How can I limit the side effects of using estrogen?
Stacy Wiegman, PharmDStacy Wiegman, PharmD
You can lower your risk of side effects from medications that contain estrogen by taking the fol...
More Answers
How does estrogen production affect puberty?
Honor Society of Nursing (STTI)Honor Society of Nursing (STTI)
At the onset of puberty, ovaries will begin to produce estrogen in girls. Estrogen will prompt the d...
More Answers
What are the side effects of conjugated estrogens?
Donna Hill Howes, RNDonna Hill Howes, RN
Side effects may include dizziness, throat or neck pain, upper abdominal pain, indigestion, nausea, ...
More Answers

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.