What should I know about estradiol gel before using it?

Estradiol gel packets are flammable, so stay away from fire and do not smoke until the application site has completely dried. Also, keep the application site dry until all the medicine has dried. Using estradiol gel for a long time increases your risk for heart attack, stroke and uterine cancer. Your doctor will try to find the most effective, lowest dose and use it for the least possible time to prevent side effects. Regular breast exams are advised. Inform all healthcare professionals that you use estradiol gel, as dental care, lab tests, surgical procedures and even bed rest may cause complications with the gel. Estradiol gel may alter your blood sugar, which may require dose changes.

You should not use this gel if you are pregnant. Estradiol gel is for external use. If it gets in your vagina, ears, eyes, nose or mouth, rinse immediately. This drug should not be used if you are pregnant or have an allergy to its ingredients, undiagnosed bleeding from the vagina or a history of heart attack, stroke, blood clots, any type of cancer, estrogen-dependent growths or liver problems. You should tell your doctor if you smoke, are going to be having surgery, have had a hysterectomy or if you take any over-the-counter or prescription medications, as many may interact with this drug.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.