Does estropipate interact with other medications or food?

The following medicines may interact with estropipate by increasing the risk of side effects or by decreasing the effectiveness of estradiol: blood thinners like warfarin; corticosteroids, such as prednisolone; barbiturates like phenobarbital; hydantoins like phenytoin; rifampin; St. John's Wort; cimetidine; carbamazepine; antibiotics like erythromycin and clarithromycin; ketoconazole or itraconazole. Grapefruit juice can decrease estrogen breakdown in the body.  

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.