Does Estrace interact with other medications or food?

Estrace does interact with food and other medications and you should ask your doctor for specific information. Grapefruit or grapefruit juice may increase estrogen levels in the blood. Estrace may interact with the following drugs:

  • aromatase inhibitors like anastrozole, exemestane, letrozole, testolactone
  • blood thinners like warfarin
  • carbamazepine
  • cimetidine
  • certain antibiotics used to treat infections like clarithromycin (Biaxin), erythromycin (E-Mycin, E.E.S., Erythrocin, Ery-Tab), ketoconazole (Nizoral) or itraconazole (Sporanox)
  • certain barbiturates or benzodiazepines used for inducing sleep or treating seizures
  • medicines for fungus infections like itraconazole and ketoconazole
  • phenytoin (Dilantin)
  • raloxifene or tamoxifen
  • rifabutin, rifater, rifamate, rifampin, rifapentine, rimactane
  • ritonavir
  • St. John's Wort

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.