Are there any risks in taking estradiol?

There are many risks in taking estradiol. You should discuss all the medical history and medications you are taking with doctor before getting a prescription for estradiol.

The major risks of taking estradiol include harming your unborn child if you are pregnant, developing endometrial hyperplasia, and increasing your risk of breast cancer, heart attack or stroke. You should not use estradiol if you are pregnant as it can lead to birth defects in the fetus.

Let your doctor know if you are pregnant or may become pregnant while using this drug. This drug also may increase your risk of developing endometrial hyperplasia. This is a condition that can cause uterine cancer. You can lower your risk of developing this condition by taking progestin at the same time you are taking estradiol. Long-term use of estradiol can increase your risk of getting breast cancer, or having a heart attack or stroke.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.