Advertisement

How effective are PDE-5 inhibitors?

Donna Hill Howes, RN
Family Practitioner

An analysis of 82 studies found that PDE-5 inhibitors were effective in 20% to 47% of men. Effectiveness was different for each drug depending on dosage, but highest dosages were not always the most effective. In general, sildenafil was the most effective and avanafil the least effective.

In two studies, tadalafil taken once daily provided treatment satisfaction comparable to PDE-5 inhibitors taken on demand. 

This answer was adapted from Sharecare's award-winning AskMD app. Start a consultation now to find out what's causing your symptoms, learn how to manage a condition, or find a doctor. 

Continue Learning about Erectile Dysfunction Treatment

How is erectile dysfunction treated if it's not related to my health?
Dr. Mehmet Oz, MDDr. Mehmet Oz, MD
If your doctor has done all the necessary tests to rule out any medical condition that might affec...
More Answers
What are the most common treatments for erectile dysfunction?
Dr. Mehmet Oz, MDDr. Mehmet Oz, MD
If you don't have an underlying condition such as serious coronary artery disease, certain eye d...
More Answers
Is It Important to Look For Psychological Causes of Erectile Dysfunction?
Is It Important to Look For Psychological Causes of Erectile Dysfunction?
Can Treatment for Erectile Dysfunction Depend on Other Conditions?
Can Treatment for Erectile Dysfunction Depend on Other Conditions?

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.