Do pancrelipase capsules interact with other drugs or food?

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Antacids containing calcium carbonate or magnesium hydroxide reduce the effectiveness of pancrelipase. On the other hand, pancrelipase may decrease the effectiveness of iron supplements. Other medications may interact with pancrelipase, and you should tell your doctor about all of the medications, including over-the-counter drugs, vitamins and herbal supplements, you are taking. Your doctor may also prescribe dietary changes to help manage your pancreatic condition. Following these recommendations in conjunction with regular use of pancrelipase will improve your digestion. You should take pancrelipase with food or immediately before meals, and drink plenty of liquids to stay hydrated.