How does Creon 5 interact with other medications or food?

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Antacids containing calcium carbonate or magnesium hydroxide reduce the effectiveness of Creon 5. On the other hand, Creon may decrease the effectiveness of iron supplements. Other medications may interact with Creon and you should tell you doctor about all of the medications, including over-the-counter drugs, vitamins and herbal supplements, you are taking. Your doctor may also prescribe dietary changes to help manage your pancreatic condition. Following these recommendations in conjunction with regular use of Creon will improve your digestion. You should take Creon with food or immediately before meals, and drink plenty of liquids to stay hydrated.