Who should not take HRT?


Women who have had a blood clot in the leg or in the lung (venous thrombosis or pulmonary embolism) within the past six months should not take hormone replacement therapy (HRT) because estrogen can increase blood clotting. Additionally, women undergoing active treatment for breast, ovarian, or uterine cancer should not take estrogen-containing hormones unless they are prescribed by an oncologist because estrogen replacement therapy (ERT) can stimulate the growth of some tumors.

Also, women with a history of gallbladder disease, severe migraine headaches, or a strong family history of either gallstones or female cancers (e.g., breast, ovarian, or uterine) should not take HRT because it may increase the risk of developing these conditions.

Continue Learning about Endocrine System

Endocrine System

Your endocrine system works with your nervous system to control important bodily functions. The endocrine systems responsibilities include regulating growth, sexual development and function, metabolism and mood. The endocrine syst...

em also helps give your body the energy it needs to function properly. Endocrine glands secrete hormones into the bloodstream. Hormones are considered chemical messengers, coordinating your body by transferring information from one set of cells to another. Your endocrine system health can be affected by hormone imbalances resulting from impaired glands. A hormone imbalance can cause problems with bodily growth, sexual development, metabolism and other bodily functions. Endocrine system diseases or conditions include diabetes, growth disorders and osteoporosis.

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.