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What is vasoactive intestinal peptide?

Vasoactive intestinal peptide (VIP) is a hormone that stimulates the secretion and inhibits the absorption of sodium, chloride, potassium, and water within the small intestine and increases bowel motility. These actions lead to a secretory diarrhea, hypokalemia (low potassium), and dehydration. A pancreatic neuroendocrine tumor which secretes vasoactive intestinal peptide (VIP) is called VIPoma. 

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