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What is a neuroendocrine tumor?

Neuroendocrine tumors arise from the neuroendocrine system, which is composed of cells that have features of both nerve cells and endocrine cells and are found though out the body. These cells share certain biochemical functions such as amine precursor uptake and decarboxylation (or APUD), hence an earlier classification referred to these tumors as APUDomas. The first neuroendocrine tumor was recognized by a German pathologist by the name of Siegfried Oberndorfer, who in 1907 coined the term carcinoid or carcimona-like, recognizing the relatively low malignant features of this unusual tumor.  

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