What are extra-adrenal pheochromocytomas?

Paragangliomas are also called extra-adrenal pheochromocytomas and these terms are often used interchangeably. Overall, it has been estimated that approximately 10% of pheochromocytomas occur in an extra-adrenal location. Compared to adrenal pheochromocytomas, paragangliomas have a higher risk of being malignant or cancerous, as high as 40-50% in some studies. Larger tumor size (over 5 cm), invasion of the tumor into adjacent structures, and spread (metastases) to other organs are characteristics of malignant paragangliomas. 

Continue Learning about Endocrine System

Endocrine System

Your endocrine system works with your nervous system to control important bodily functions. The endocrine systems responsibilities include regulating growth, sexual development and function, metabolism and mood. The endocrine syst...

em also helps give your body the energy it needs to function properly. Endocrine glands secrete hormones into the bloodstream. Hormones are considered chemical messengers, coordinating your body by transferring information from one set of cells to another. Your endocrine system health can be affected by hormone imbalances resulting from impaired glands. A hormone imbalance can cause problems with bodily growth, sexual development, metabolism and other bodily functions. Endocrine system diseases or conditions include diabetes, growth disorders and osteoporosis.

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.