What are the negative effects of hormone treatment?

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The following are the negative effects of hormone treatment:

  • Bleeding
  • Bloating
  • Breast tenderness or enlargement
  • Headaches
  • Nausea
  • Vaginitis and vaginal itching
  • Leg cramps
  • Menstrual cramps
  • Mood changes

The negative effects of hormone treatment vary considerably among women, and the severity and frequency differ as well. Some women have no negative effects; other women experience minor problems, while still others can't take the drugs because the unwanted effects are so strong.

The type of hormone treatment a woman is taking—estrogen only or a combination of estrogen plus progestogen—as well as the dose may determine the effects experienced. If you are having problems, it may be helpful to try a lower dose.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.