How can I manage the side effects of hormone replacement therapy (HRT)?


Most side effects related to hormone replacement therapy (HRT) improve within a few months of therapy or can be alleviated by switching to another formulation.

Side effects related to estrogen (e.g., nausea, headache, or breast tenderness) can often be alleviated by temporarily reducing the dose of estrogen; switching from cyclic to continuous therapy (i.e., taking progesterone every day along with estrogen, rather than only 10 to 14 days each month); or using an estrogen patch rather than taking estrogen in pill form.

Side effects related to progesterone (e.g., headache, breast tenderness, irritability, or depressed moods) can be countered by switching from cyclical to continuous therapy or from Provera to another formulation of progesterone.

Continue Learning about Endocrine System

Endocrine System

Your endocrine system works with your nervous system to control important bodily functions. The endocrine systems responsibilities include regulating growth, sexual development and function, metabolism and mood. The endocrine syst...

em also helps give your body the energy it needs to function properly. Endocrine glands secrete hormones into the bloodstream. Hormones are considered chemical messengers, coordinating your body by transferring information from one set of cells to another. Your endocrine system health can be affected by hormone imbalances resulting from impaired glands. A hormone imbalance can cause problems with bodily growth, sexual development, metabolism and other bodily functions. Endocrine system diseases or conditions include diabetes, growth disorders and osteoporosis.

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.