What is a sestamibi scan for primary hyperparathyroidism?

In most patients with primary hyperparathyroidism (80%), only one of the four parathyroid glands is diseased. Localizing tests are radiology tests designed to help identify which parathyroid gland(s) are hyperactive. One such localizing test is a sestamibi scan which involves injecting a small amount of special radioactive material into a vein and taking an X-ray image of the chest, neck, and head. The advantages of a sestamibi scans are their widespread availability and their ability to evaluate for diseased glands outside of the neck.
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Parathyroid Gland

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