Endocrine-Metabolic Agent

Endocrine-Metabolic Agent

Endocrine-Metabolic Agent
Endocrine drugs treat endocrine problems and disorders such as hormone production, thyroid disorders an diabetes.

Recently Answered

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    When you stop taking Prempro, your menopausal symptoms may return. Also, you will likely have some bone loss. Talk to your doctor about ways to minimize bone loss and other ways to relieve your symptoms. Make sure any alternative treatments you may take have been approved by the Food and Drug Administration.

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    There are certain precautions you should be aware of before taking conjugated estrogens and medroxyprogesterone acetate. The medication may cause harmful reactions with certain medical conditions, including liver, heart, kidney, or gall bladder disease, cancer, diabetes, high blood pressure, epilepsy, asthma, jaundice, lupus, clots in the blood vessels, fibroids, genital bleeding, or migraines. Similarly, some medications may react poorly with conjugated estrogens and medroxyprogesterone acetate, including acetaminophen, morphine, St. John’s wort, certain steroids, thyroid medicines, antibiotics, blood thinners, anti-fungal and anti-seizure medications, and breast cancer drugs like exemestane and anastrozole. Also, conjugated estrogens and medroxyprogesterone acetate may increase your risk of ailments like uterine and breast cancer, strokes, heart attacks, and blood clots. Smoking may increase your risk of these side effects. Pregnant women should not use the medication, as it could cause damage to your child's health. Additionally, you should alert your doctor if you are breastfeeding, as your milk can be affected. Finally, taking conjugated estrogens and medroxyprogesterone acetate may affect the outcome of certain lab tests, so let lab technicians know you are taking the medication before undergoing testing.
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    A , Pharmacy, answered

    You should not smoke cigarettes while taking Prempro. Smoking may increase your risk of serious side effects such as blood clots and stroke. It also may cause your Prempro to be less effective in relieving your menopausal symptoms. Let your doctor know you smoke cigarettes and discuss how that may impact your hormone replacement therapy.

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    A , Pharmacy, answered
    Long-term use of Prempro is associated with an increased risk of breast cancer, heart disease, stroke, blood clots, and dementia. Before taking Prempro, tell your doctor if you have an estrogen-dependent tumor, abnormal vaginal bleeding, active or recent stroke or heart attack, circulation problems, a history of blood clots, or liver disease. While taking Prempro, you should consult with your doctor every three to six months so that he or she can monitor your symptoms, and reevaluate your need for this medication. Prempro should be taken at the lowest dose and for the shortest period of time necessary to relieve menopausal symptoms.
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    A , Pharmacy, answered

    Prempro relieves menopausal symptoms because the estrogens in Prempro replace those no longer produced by the ovaries. The progesterone component in Prempro protects menopausal women with an intact uterus from the risk of uterine cancer. In addition, because estrogen keeps the bones strong, replacing the estrogen lost during menopause helps reduce the risk of osteoporosis. Prempro should be used at the lowest dose and for the shortest period of time necessary to relieve menopausal symptoms and prevent osteoporosis.

     

    While taking Prempro, you will not have a monthly menstrual period. You may have intermittent bleeding and spotting, however, although this should stop over time. If you prefer to have a monthly period, Premphase, a hormone replacement therapy which provide progesterone only during the last half of the cycle, may be a better choice for you.
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    A , Pharmacy, answered

    Despite numerous studies, it is still uncertain if taking Prempro, or other combination hormone replacement therapy, increases your risk of endometrial cancer. Some studies suggest that the risk may be lower than taking an estrogen-only therapy, but higher than not taking any hormone replacement therapy. Your risk of cancer changes as you age, so talk to your doctor regularly about your health, risks and hormone replacement therapy.

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    A , Pharmacy, answered

    Studies and research have yet to determine if hormone replacement therapy increases your risk of breast cancer. Breast tenderness and pain have been reported. It is uncertain whether Prempro will contribute to your risk of breast cancer, so you should do a self breast exam monthly. Be sure to note any unusual lumps or discharge. You should also have a mammogram regularly, or as prescribed by your doctor. Report any changes to your doctor and talk to your doctor about your breast cancer risk.

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    The U.S. Food and Drug Administration (FDA) recommends that you take hormones such as Prempro for the shortest amount of time possible. They also advise that you try the lowest dose of hormones to relieve your symptoms. Talk to your doctor about the length of your hormone replacement therapy and how to transition from using prempro.

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    Prempro may interact with grapefruit and grapefruit juice. It can also interact with the herbal supplement St. John’s wort. In addition, the effectiveness of Prempro may be decreased by aminogluthethimide, hydantoins, or rifampin; Prempro may decrease the effectiveness of anticoagulants or increase their risk of side effects; and Prempro may increase the risk of side effects associated with corticosteroids or succinylcholine.
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    A , Pharmacy, answered
    Prempro comes in a package of 28 tablets containing both estrogen and progesterone. Prempro is most effective if taken at the same time each day. You can take it with a full glass of water at meal times to avoid stomach upset.