Why do I need a glucagon shot if I have severe hypoglycemia?

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People who take insulin are at risk for episodes of severe hypoglycemia. During such an episode, brain cells don't get the fuel (glucose) they need. Unless their blood glucose is quickly raised, it can cause brain damage -- even death. Glucagon is one way to quickly raise blood glucose. It's a natural hormone that helps the liver release glucose into the bloodstream. It's the fastest and safest way to raise blood glucose when the person is unconscious.