What side effects does raloxifene (Evista) cause?

As with any medication, you may have unwanted side effects from taking raloxifene. The more common ones include hot flashes as well as cramps or spasms in your leg muscles. Other possible side effects include swelling in your legs or arms (called edema), joint pain, feeling like you have the flu, rash, abdominal pain, sore throat, vaginal bleeding or breast pain.

Serious side effects -- strokes, blood clots in the lungs (pulmonary embolism), blood clots in the legs or arms (deep vein thrombosis) or blood clots in the vessels at the back of the eye (retinal vein thrombosis) -- are, fortunately, rare.

Based on information from, a free medication monitoring service, 10% of patients experience side effects while taking Raloxifene (Evista). Some of the side effects reported by iGuard members include: Hot Flashes, and Muscle Pain/Cramps. Please follow up with your doctor or other healthcare provider if you are experiencing any symptoms that worsen or do not go away.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.