Does Prempro interact with other medications or foods?

Prempro may interact with grapefruit and grapefruit juice. It can also interact with the herbal supplement St. John’s wort. In addition, the effectiveness of Prempro may be decreased by aminogluthethimide, hydantoins, or rifampin; Prempro may decrease the effectiveness of anticoagulants or increase their risk of side effects; and Prempro may increase the risk of side effects associated with corticosteroids or succinylcholine.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.