Does Premphase interact with other medications or foods?

Advertisement
Advertisement
Premphase may interact with grapefruit and grapefruit juice. It can also interact with the herbal supplement St. John’s wort. In addition, the effectiveness of Premphase may be decreased by aminogluthethimide, hydantoins, or rifampin; Premphase may decrease the effectiveness of anticoagulants or increase their risk of side effects; and Premphase may increase the risk of side effects associated with corticosteroids or succinylcholine.