What should I know about Increlex before using it with my child?


Before using Increlex for your child, it is important to know that this form of IGF-1 medication is man-made. It is similar to a naturally occurring substance in the body that promotes muscle and bone growth. When a child has low levels of IGF-1, Increlex may be prescribed to increase those levels. Do not give this medication if your child is allergic to mecasermin, has cancer or has stopped growing and the growth plates are closed. It should also not be given to a child with malnutrition, underactive thyroid, if the child has a growth hormone deficiency or is on long-term steroid medications.

If prescribed, you will need to inject your child with daily doses. Your doctor will show you how to give this injection twice daily. Rotate sites for each injection, between your child's thigh, upper arm, stomach or buttocks. Use each needle only one time and do not use the medication if it has changed colors or if it has particles in it. Each injection should be given with food, especially within 20 minutes before or after the injection. This type of medicine can cause a drop in blood sugar levels, so it is important to keep a snack, juice or milk nearby if your child begins to show symptoms of hypoglycemia (low blood sugar). Before using Increlex to treat your child, it is important that you are able to recognize hypoglycemia symptoms, which include:

  • confusion
  • difficulty concentrating
  • drowsiness
  • dizziness
  • headaches
  • blurred vision
  • fainting
  • hunger
  • weakness
  • irregular heartbeat
  • irritability
  • nausea
  • seizure (convulsions)
  • sweating
  • tremors

In severe cases hypoglycemia can lead to seizures or coma.