How does Activella treat osteoporosis?

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Patricia Geraghty, NP
Women's Health
Activella is a tablet that contains an estrogen in the form of estradiol and a progestin called norethindrone acetate. This progestin has been used for many years in birth control pills. The dose in activella is a lower dose for use in women who are menopausal.
Estrogen has been shown to keep bones from losing mass and to prevent fractures, in particular hip fractures. It prevents osteoporosis. It is not the best medication to use if osteoporosis is already present. The bone support is not permanent. Unfortunately, when the estrogen is discontinued, bone loss speeds up again. The progestin protects the uterus from stimulation by the estrogen, preventing uterine cancer.
The benefits and risks of using hormone therapy in menopause found in studies on similar products apply to Activella also. There is an increased risk of blood clots in the vessels and, with prolonged use or use into your 60's, a risk of breast cancer.

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