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When should I call my doctor about problems taking prempro?

If you are taking Prempro, you should call your doctor if you experience any of the following symptoms:

  • severe breast pain and tenderness
  • swelling of feet or legs
  • rapid weight gain
  • vaginal bleeding
  • dizziness or lightheadedness
  • headaches
  • calf pain
  • speech problems
  • dark urine
  • yellowing of the skin
  • dark stool
  • rash
  • fever

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.