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Debra Fulghum Bruce PhD, Healthcare, answeredSweet bell peppers, as well as spicy chile peppers, are filled with the phytochemical capsaicin, which packs an impressive punch against inflammation. Capsaicin reduces levels of substance P, the compound in the body that triggers inflammation and pain impulses from the central nervous system. It is also thought that this pain-relieving phytochemical triggers the body to release endorphins, nature’s own opiates. Red peppers are also filled with salicylates, which are aspirin-like compounds.