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Can PolyGlycopleX (PGX) help in fighting metabolic syndrome?

Michael T. Murray, ND
Naturopathic Medicine

The underlying physiological defect in the metabolic syndrome is insulin resistance and its accompanying elevated insulin levels. PolyGlycopleX (PGX) has been shown to improve significantly all aspects of the metabolic syndrome. At the annual meeting of the American Diabetes Association in 2004, the results of a clinical study using this proprietary fiber blend were presented by researchers from the Risk Factor Modification Centre at St, Michael's Hospital and the University of Toronto. Subjects with the metabolic syndrome took 3 grams of PGX or a placebo three times a day before meals. After three weeks, there was a 23 percent reduction in after-meal glucose levels, a 40 percent reduction in after-meal insulin release, and a 55.9 percent improvement in whole body insulin sensitivity scores in the group taking PGX. In addition, body fat was reduced by 2.8 percent from baseline over the three-week study period.

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