Can I become immune to botulinum neurotoxin?

Research suggests that there may be cumulative benefit to long-term treatment with botulinum neurotoxin therapy. However, in some cases, individuals who have been successfully treated with botulinum neurotoxin therapy begin to experience a loss in benefit. Several factors may be responsible for this change. The nature and pattern of the dystonia may change over time and require an adjustment in the site of injection and dosage. If deep muscles become involved, it may be difficult to access them. It is also helpful to have the same physician administer your injection each time, if possible. Tell your doctor if you notice a change in how your symptoms respond to botulinum neurotoxin therapy.

Continue Learning about Dystonia


When your muscles contract involuntarily, the condition is called dystonia. Dystonia causes a twisting or clenching of whatever body part is affected. For example, when you have a stroke, the affected arm and hand may be clenched ...

and held in a strange position. Dystonia can be very mild or very severe. It can make your life very difficult and this can lead to frustration, depression or anxiety. See your doctor to treat your symptoms and talk over your frustrations.

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.