What should I know about eplerenone before taking it?

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You need to keep taking eplerenone, even if you feel well, because hypertension is often asymptomatic. You should also make sure that you attend all of your follow-up appointments, because you need to be monitored to make sure that eplerenone is not harming you and is successfully treating your condition. While taking eplerenone, do not take any potassium supplements or salt substitutes, unless you are instructed otherwise by your doctor. You should keep your doctor informed about all of the medications and herbal products that you are currently taking or intend to take while taking eplerenone.

Certain substances should not be taken at the same time as eplerenone, without the express permission of your doctor. These include: ritonavir, troleandomycin, nelfinavir, nafazodone, itraconazole, ketconazole and clarithromycin. If you have a severe kidney disease, type 2 diabetes with protein in your urine or high potassium levels in your blood, your doctor may tell you not to take eplerenone. Make sure your doctor is aware that you have any of these conditions or if you have a liver disease, high triglycerides or high cholesterol.