What precautions are necessary before taking spironolactone?

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Before you start taking spironolactone, tell your doctor if any of the following conditions apply to you:
  • You have allergies involving spironolactone or other medications
  • You have a history of heart, kidney or liver disease
  • You use other diuretics or steroids
  • You have high levels of potassium in the blood (hyperkalemia) or
  • You are pregnant or breastfeeding
While taking spironolactone, you will have to monitor and control your diet as an imbalance of either sodium or potassium levels can decrease spironolactone's efficiency. It is important to maintain a balance of hydration during spironolactone treatment. Because drinking too much or too little water during treatment can be dangerous, it is crucial to follow your doctor's advice closely. People with high blood pressure who are being treated with spironolactone must continue taking their medication even if they feel better.