What is amiloride-hydrochlorothiazide?

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Amiloride and hydrochlorothiazide are prescribed together to treat high blood pressure and water retention (edema). This is because both medications are diuretics, also called "water pills". Diuretics promote urination, reducing the amount of water and salt in the body. This can help lower blood pressure and control edema. It is sold under the brand name Moduretic.