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What is amiloride and hydrochlorothiazide?

Amiloride-hydrochlorothiazide is a combination of two active ingredients used as a treatment for high blood pressure, edema (fluid retention) and heart failure. Amiloride is called a potassium-sparing diuretic and it increases water and sodium excretion with decreased excretion of potassium in the urine. Hydrochlorothiazide, abbreviated HCTZ, is called a thiazide diuretic that increases water excretion with increased excretion of sodium in the urine. The combination works by reducing blood volume as the excess water is excreted.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.